T1D Pregnancy & Me
T1D Pregnancy & Me will partner with pregnant participants living with type 1 diabetes
(T1D) in the United States to collect real-world data on management of T1D in pregnancy.
This is a remote study where participants can complete online surveys and share device
data...
Age: 18 years - 66+
Gender: Female
HLA Demographics Study in Adults With Type 1 Diabetes
This is a study to evaluate the HLA-DRB1*04:01 genotype in adults that have been diagnosed with type 1 diabetes
Age: 18 - 45 years
Gender: All
Innovative Automated Insulin Delivery System for Type 2 Diabetes
The goal of this clinical trial is to learn if the twiist insulin delivery system works to treat adults with insulin-treated type 2 diabetes.
Age: 18 years - 66+
Gender: All
Glucose Frequent of A1GDM in Labor
This is a prospective double arm study in patients with Gestational Diabetes Mellitus
(GDM) utilizing frequent (single fingerstick on admission) vs infrequent glucose
monitoring in labor (q 4 hours in latent labor and every 2 hours in active labor).
Primary Objective...
Age: 18 years - 66+
Gender: Female
Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes
Pregnant women aged 18-40 with gestational diabetes (GDM) will take part in this study.
We want to see how two different insulin treatments affect their blood sugar after they
eat. These women usually use a rapid-acting insulin analog (RAA) that's injected to
control...
Age: 18 - 40 years
Gender: Female
Frequency of Glucose Monitoring in Labor
The aim of this study is to assess rates of neonatal hypoglycemia with differing
intrapartum glucose protocols. Currently at this time there is no guidance from
professional medical organizations about when and how frequent to assess maternal glucose
levels intrapart...
Age: 18 years - 66+
Gender: Female
Cholesterol Lowering and Residual Risk in Diabetes, Type 1
This is a prospective, interventional, cohort study, meaning that researchers will follow
and observe a group of enrolled study participants over a period of time (one to two
months) to gather information and record any developments of the outcomes in question.
Thi...
Age: 18 - 89 years
Gender: All
Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients
The clinical benefits of the dual Sodium-Glucose cotransporter (SGLT) 1 and 2-inhibition
have recently been reported in two clinical trials. The SOLOIST reported the benefits of
sotagliflozin in Type-2 Diabetes Mellitus (T2DM) patients hospitalized for worsening of
H...
Age: 18 years - 66+
Gender: All
Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Improving Glycemic Control in Adults With Type 2 Diabetes Mellitus
Trial Title A randomized, double blind sham controlled clinical trial to evaluate the
efficacy of vestibular nerve stimulation (VeNS), together with a lifestyle modification
program, compared to a sham control with a lifestyle modification program, as a means of
i...
Age: 22 - 70 years
Gender: All
Prediabetes and Type 2 Diabetes Data Collection Study
To collect data in an observational study from Prediabetes (PD) and Type 2 Diabetes (T2D)
patients including time correlated CGM, medication and food intake approximately 80% of the
time for each subject that completes the entire active phase.
Age: 18 years - 66+
Gender: All
Evaluation of the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects With Type 2 Diabetes on Insulin Therapy
The Revita® system is being investigated to assess the efficacy of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled with insulin therapy. The purpose of this study is t...
Age: 21 - 70 years
Gender: All
Longitudinal Observation of Insulin Requirements and Sensor Use in Pregnancy
The overall goal of this study is to enroll pregnant women with type 1 diabetes and follow their glycemic outcomes prospectively throughout pregnancy and into the post-partum period. The investigators anticipate that when compared to subjects using an Artificial pancrea...
Age: 18 - 40 years
Gender: Female
EMPEROR-HF: A phase III randomised, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction (HFrEF)
Chronic heart failure (HF) is a progressive syndrome characterized by the inability of the heart to provide adequate blood supply to meet the metabolic demand of different tissues or to be able to do so only at the expense of elevated left ventricle filling pressure. HF...
Age: 18 - 45 years
Gender: All
A Trial Comparing Insulin Degludec and Glargine U100 for Management of Hospitalized and Discharged Patients With Type 2 Diabetes
The purpose of this study is to find out if treatment with Degludec insulin when compared to
glargine U100 insulin will result in similar blood sugar control in patients with diabetes,
who are admitted to the hospital and then transition at home, after discharge from ...
Age: 18 years - 66+
Gender: All
PriMatrix for the Management of Diabetic Foot Ulcers
The study will evaluate the efficacy of PriMatrix Dermal Repair Scaffold in the management of diabetic foot ulcers in subjects with diabetes mellitus versus the Standard of Care treatment. Half of patients will be treated using PriMatrix while the other half will receiv...
Age: 18 years - 66+
Gender: All
Study of Procoagulation Markers in Stroke Patients
The Insights on Selected Procoagulation Markers and Outcomes in Stroke Trial (I-SPOT): Response to Insulin Administration and Blood Glucose Control proposal is designed to accompany the Stroke Hyperglycemia Insulin Network Effort (SHINE) clinical trial, a Phase III mult...
Age: 18 years - 66+
Gender: All